Which two medications are commonly used as painkillers for horses?

The selection of Bute and Banamine as commonly used painkillers for horses is based on their effectiveness and veterinary approval. Phenylbutazone, often referred to as "bute," is a non-steroidal anti-inflammatory drug (NSAID) widely used in equine medicine to alleviate pain and reduce inflammation associated with various ailments, including musculoskeletal issues. It is specifically approved for use in horses, making it a trusted choice among veterinarians.

Banamine, or flunixin meglumine, is another NSAID that is particularly effective in treating colic pain and controlling fevers in horses. It provides both analgesic and anti-inflammatory effects, making it suitable for managing acute pain conditions. The combination of these two medications covers a range of pain management needs in horses, especially in competitive and performance contexts.

In contrast to the other options, which either include medications not specifically indicated for horses (like ibuprofen and acetaminophen, which are not safe for equine use) or suggest alternatives that are less commonly used in equine practice, the pair of Bute and Banamine remains the best recognized for their safety and efficacy in providing pain relief for horses.